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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MBD4
All Species:
4.55
Human Site:
S122
Identified Species:
11.11
UniProt:
O95243
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95243
NP_003916.1
580
66051
S122
G
L
K
F
R
S
K
S
S
L
A
N
Y
L
H
Chimpanzee
Pan troglodytes
XP_001144095
580
66029
S122
G
L
K
F
R
S
K
S
S
L
A
N
Y
L
H
Rhesus Macaque
Macaca mulatta
XP_001116090
537
61569
G97
A
N
Y
L
H
K
N
G
E
T
C
L
K
P
E
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2D7
554
62559
R106
S
P
Q
G
L
K
F
R
S
K
R
S
L
A
N
Rat
Rattus norvegicus
Q00566
492
53029
H52
P
L
Q
P
S
A
H
H
S
A
E
P
A
E
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506061
435
49137
Chicken
Gallus gallus
NP_990024
416
45436
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783908
550
62272
V103
T
P
L
K
K
R
K
V
S
L
A
E
E
E
P
Poplar Tree
Populus trichocarpa
XP_002331937
249
28474
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_974253
445
51117
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
86.7
N.A.
N.A.
65.6
23.4
N.A.
34.4
39.8
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
29.3
Protein Similarity:
100
99.8
88.2
N.A.
N.A.
73.9
37.9
N.A.
46
49.8
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
45.3
P-Site Identity:
100
100
0
N.A.
N.A.
6.6
13.3
N.A.
0
0
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
P-Site Similarity:
100
100
0
N.A.
N.A.
26.6
26.6
N.A.
0
0
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
20
N.A.
N.A.
23.1
N.A.
N.A.
Protein Similarity:
28.9
N.A.
N.A.
38.6
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
0
N.A.
N.A.
0
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
10
0
0
0
10
30
0
10
10
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
10
0
10
10
10
20
10
% E
% Phe:
0
0
0
20
0
0
10
0
0
0
0
0
0
0
0
% F
% Gly:
20
0
0
10
0
0
0
10
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
10
0
10
10
0
0
0
0
0
0
20
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
20
10
10
20
30
0
0
10
0
0
10
0
0
% K
% Leu:
0
30
10
10
10
0
0
0
0
30
0
10
10
20
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
0
0
10
0
0
0
0
20
0
0
10
% N
% Pro:
10
20
0
10
0
0
0
0
0
0
0
10
0
10
10
% P
% Gln:
0
0
20
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
20
10
0
10
0
0
10
0
0
0
0
% R
% Ser:
10
0
0
0
10
20
0
20
50
0
0
10
0
0
0
% S
% Thr:
10
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
0
0
0
0
0
0
0
20
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _